Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > News > Artificial nanopores take analyte pulse

July 31st, 2007

Artificial nanopores take analyte pulse

Abstract:
Resistive pulse sensing represents a very attractive method for identifying and quantifying biomedical species such as drugs, DNA, proteins, and viruses in solution. This method involves measuring changes in the ionic current across a membrane containing a single nanometer-sized pore that separates two electrolyte solutions. As the biological analytes make their way through the pore, they induce transient downward current pulses in the ionic current by transiently blocking the nanopore.

The frequency, duration, and magnitude of the current pulse contain telltale information that aids the identification and quantification of the analyte. A biological nanopore, α-hemolysin, supported by a lipid bilayer membrane, works well in the detection of various analytes. However, a major impediment to this system is its lack of mechanical robustness. Indeed, these biological membranes tend to rupture within a few hours, thus precluding their application in practical sensing devices.

Now a team of researchers at the University of Florida have come up with a major breakthrough that will aid the reproducible fabrication of robust synthetic single-nanopore membranes ("A Method for Reproducibly Preparing Synthetic Nanopores for Resistive-Pulse Biosensors").

Source:
nanowerk.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Sensors

Innovative sensing platform unlocks ultrahigh sensitivity in conventional sensors: Lan Yang and her team have developed new plug-and-play hardware to dramatically enhance the sensitivity of optical sensors April 5th, 2024

$900,000 awarded to optimize graphene energy harvesting devices: The WoodNext Foundation's commitment to U of A physicist Paul Thibado will be used to develop sensor systems compatible with six different power sources January 12th, 2024

A color-based sensor to emulate skin's sensitivity: In a step toward more autonomous soft robots and wearable technologies, EPFL researchers have created a device that uses color to simultaneously sense multiple mechanical and temperature stimuli December 8th, 2023

New tools will help study quantum chemistry aboard the International Space Station: Rochester Professor Nicholas Bigelow helped develop experiments conducted at NASA’s Cold Atom Lab to probe the fundamental nature of the world around us November 17th, 2023

Discoveries

Virginia Tech physicists propose path to faster, more flexible robots: Virginia Tech physicists revealed a microscopic phenomenon that could greatly improve the performance of soft devices, such as agile flexible robots or microscopic capsules for drug delivery May 17th, 2024

Diamond glitter: A play of colors with artificial DNA crystals May 17th, 2024

Finding quantum order in chaos May 17th, 2024

Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, shows quartet of new studies May 17th, 2024

Announcements

Virginia Tech physicists propose path to faster, more flexible robots: Virginia Tech physicists revealed a microscopic phenomenon that could greatly improve the performance of soft devices, such as agile flexible robots or microscopic capsules for drug delivery May 17th, 2024

Diamond glitter: A play of colors with artificial DNA crystals May 17th, 2024

Finding quantum order in chaos May 17th, 2024

Oscillating paramagnetic Meissner effect and Berezinskii-Kosterlitz-Thouless transition in cuprate superconductor May 17th, 2024

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books



NNN
The Hunger Project