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March 27th, 2006

Nanoparticles Image Sentinel Lymph Nodes

Abstract:
Patients who have breast cancer, melanoma or gastrointestinal cancer typically undergo sentinel lymph node biopsy prior to surgery in order to first determine whether the patient’s cancer has spread beyond its primary site. Several different nanoparticle formulations may be able to provide a fast, sensitive method for assaying lymph nodes by allowing various imaging technologies to spot metastases either without the need for surgical biopsy or during surgery to remove the primary cancer. Now, two reports show that nanoparticle-based imaging agents do indeed promise improved detection of metastases using either magnetic resonance imaging (MRI) or optical imaging.

Source:
nano.cancer.gov

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