Home > Press > Researcher Bilgicer using nanotechnology to improve cancer treatment
 |
| Basar Bilgicer, assistant professor of chemical and biomolecular engineering |
Abstract:
Research directed by Basar Bilgicer, assistant professor of chemical and biomolecular engineering and a member of the Advanced Diagnostics and Therapeutics initiative at the University of Notre Dame, could one day enable clinicians to deliver powerful chemotherapy drugs to tumors without deleterious side effects.
Researcher Bilgicer using nanotechnology to improve cancer treatment
Notre Dame, IN | Posted on December 6th, 2010Although chemotherapeutic agents are poisonous to tumors, they also can kill healthy cells, leading to toxic side effects.
Bilgicer's research involves developing drug-loaded nanoparticles to target the tumor tissue, so that the chemotherapeutic agents can be delivered specifically to the tumors rather than healthy tissue.
His studies are based on the fact that nanoparticles accumulated in the tumor tissue, whose leaky blood vessels allowed the nanoparticles to pass out of the capillaries that feed the tumor. While the nanoparticles are small enough to penetrate the tumor tissue, they are too large to pass into other tissues in vital organs such as the kidneys, lungs, liver or spleen. Once the molecule is firmly lodged in the tumor, the higher acidity of the tumor environment causes the release of the chemotherapeutic load, thereby dumping its toxicity fully on cancerous tissues rather than traveling to healthy cells.
Although Bilgicer's studies have primarily been in blood cancers, he notes that the nanoparticles also have application in lung and breast cancers. The nanoparticles will require further development and clinical trials before they are ready for patient care.
Bilgicer will be collaborating with Rudolph Navari, director of Notre Dame's Walter Cancer Institute and assistant dean of the Indiana University School of Medicine South Bend, to study the compound's possible uses in oncology treatment.
####
For more information, please click here
Contacts:
Basar Bilgicer
574-631-1429
Copyright © University of Notre Dame
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Beyond wires: Bubble technology powers next-generation electronics:New laser-based bubble printing technique creates ultra-flexible liquid metal circuits November 8th, 2024
Nanoparticle bursts over the Amazon rainforest: Rainfall induces bursts of natural nanoparticles that can form clouds and further precipitation over the Amazon rainforest November 8th, 2024
Nanotechnology: Flexible biosensors with modular design November 8th, 2024
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Videos/Movies
New X-ray imaging technique to study the transient phases of quantum materials December 29th, 2022
Solvent study solves solar cell durability puzzle: Rice-led project could make perovskite cells ready for prime time September 23rd, 2022
Scientists prepare for the world’s smallest race: Nanocar Race II March 18th, 2022
Visualizing the invisible: New fluorescent DNA label reveals nanoscopic cancer features March 4th, 2022
Possible Futures
Nanotechnology: Flexible biosensors with modular design November 8th, 2024
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Turning up the signal November 8th, 2024
Nanofibrous metal oxide semiconductor for sensory face November 8th, 2024
Academic/Education
Rice University launches Rice Synthetic Biology Institute to improve lives January 12th, 2024
Multi-institution, $4.6 million NSF grant to fund nanotechnology training September 9th, 2022
Nanomedicine
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Unveiling the power of hot carriers in plasmonic nanostructures August 16th, 2024
Announcements
Nanotechnology: Flexible biosensors with modular design November 8th, 2024
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Turning up the signal November 8th, 2024
Nanofibrous metal oxide semiconductor for sensory face November 8th, 2024
Nanobiotechnology
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
The mechanism of a novel circular RNA circZFR that promotes colorectal cancer progression July 5th, 2024
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||